PROBLEM TO BE SOLVED: To provide a composition for treating and/or preventing age related macular degeneration and eye disorders of other conditions involving macular degeneration, choroidal neovascularization, and/or retinal neovascularization.SOLUTION: The present invention relates to a method of treating eye disorder using a compstatin of a cyclic peptide, that binds to a specific complement component C3 and inhibits complement activity, and a complement inhibiting analog thereof. The present invention also relates to the composition comprising the compstatin or the complement inhibiting analog thereof and a gel-forming material, for example, soluble collagen, as well as the method of administering the composition and inhibiting a complement classical pathway and/or a complement alternate pathway.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】加齢性黄斑変性症並びに黄斑変性症、脈絡膜血管新生及び/又は網膜血管新生を含む他の状態の眼の障害を処置及び/又は予防するための組成物の提供。【解決手段】特定の補体成分C3に結合し、補体活性化を阻害する環状ペプチドのコンプスタチン及びその補体阻害アナログを使用する眼の障害を処置する方法。また、コンプスタチン又はその補体阻害アナログ及びゲル形成材料、例えば可溶性コラーゲンを含む組成物並びにその組成物を投与し、補体古典的経路及び/又は補体副経路を阻外する方法。【選択図】なし
