CHEN, CHIA NAN,陈嘉南,陳嘉南,CHEN, JIA SHIONG,陈嘉雄,陳嘉雄,CHAO, YE SU,赵月秀,趙月秀,WU, YI HONG,吴奕宏,吳奕宏,CHI, LI LING,纪俐伶,紀俐伶
申请号：
TW105123349
公开号：
TW201718021A
申请日:
2016.07.22
申请国别(地区):
TW
年份:
2017
代理人:
摘要：
The invention is based on at least a discovery of a metallic nanoparticle that can simultaneously bind pH-sensitive linker, antibodies and PEGs to form a complex. The complex of the invention can deliver the antibody to the targeting cells involved in disease processes or close to cells so that the antibody can selectively target and effect on the cells.本發明係基於至少發現一種金屬奈米粒子，其可同時結合pH敏感性連接物、抗體及PEG以形成複合物。本發明之複合物可將該抗體傳遞至疾病過程中所涉及之靶細胞或接近細胞，以使該抗體可選擇性地靶向及作用於該等細胞。
