The invention discloses a disposable endoscope protection sleeve, which comprises: a buffer sleeve which is hollow and has an opening at one end for the endoscope to enter from the opening, and the buffer sleeve is provided therein At least one elastic supporting portion for clamping different sizes of the endoscope; and a hose having one end connected to the buffer sleeve with respect to one end of the opening and communicating with the buffer sleeve. In this way, the disposable endoscope protective sleeve provided by the present invention can allow different sizes of endoscopes to be stably placed in the protective sleeve by different types of elastic supporting portions, so that the user only A disposable through-the-lens protection sleeve is available for a wide range of different sizes of endoscopes to reduce waste and increase waste.本發明揭露一種拋棄式內視鏡保護套管,其包含:一緩衝套,其係為中空且一端係具有一開口,以供內視鏡從該開口處進入,而該緩衝套內係設有至少一彈性支撐部,以供夾固不同尺寸的內視鏡;及一軟管,其一端係與該緩衝套相對於設有該開口之一端連接並與該緩衝套內連通。如此一來,本發明所提供之拋棄式內視鏡保護套管藉由不同形式的彈性支撐部就能讓不同尺寸的內視鏡皆可穩定置入在保護套管內,以使使用者只需使用一種尺寸之拋棄式內視鏡保護套管便可適用於各種不同尺寸的內視鏡,以在減少成本花費上又能避免廢棄物增加。