Public Joint Stock Company " Scientific Industrial Centre Borshchahivskiy Chemical Pharmaceutical Pl
发明人:
Sergii Fesenko,Alexander Shneider,Vladimir Gabai
申请号：
US16226795
公开号：
US20200200776A1
申请日:
2018.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are methods to determine the safety of quercetin compositions regarding contaminants that can result from the degradation of quercetin, such as by storage of solid form quercetin compositions in an air atmosphere. The contaminants include protocatechuic acid, 2,4,6-trihydroxybenzoic acid, and 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoic acid. Provided herein are also methods which reduce degradation of solid form quercetin compositions and reduce the formation of such toxic compounds. The provided methods increase the shelf life and patient safety of quercetin compositions.
