SOLUBILIZED CAPSULE FORMULATION OF 1,1-DIMETHYLETHYL [(1S)-1-{[(2S,4R)-4-(7-CHLORO-4METHOXYISOQUINOLIN-1-YLOXY)-2-({(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}CARBAMOYL)PYRROLIDIN-1-YL]CARB ON YL}-2,2-DIMETHYLPROPYL]CARBAMATE

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专利权人:

BRISTOL-MYERS SQUIBB HOLDINGS IRELAND

发明人:

PERRONE, ROBERT KEVIN

申请号：

PH12014502405

公开号：

PH12014502405A1

申请日:

2014.10.27

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

The present disclosure includes various embodiments directed to a solubilized capsule formulation of asunaprevir, 1,1-dimethylethyl [(1S)-1-{[(2S,4R)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrr olidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate, and to methods including asunaprevir.

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