The Board of Trustees of the University of Arkansas
发明人:
Daniel Fologea,Ralph Henry,Greg Salamo,Yuriy Mazur,Michael J. Borrelli
申请号：
US14357038
公开号：
US09849087B2
申请日:
2012.11.08
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.
