PROBLEM TO BE SOLVED: To provide an isolator system cable of appropriate decontamination work in the case of being used in connected state of a plurality of systems.SOLUTION: An isolator system comprises: work boxes 110, 210 which are connectable to another isolator system, and surround sealed workspaces 111, 211 pass boxes 120, 220 which are communicably connected to the work boxes 110, 210 and a sterilization part which sterilizes the inside of the pass boxes 120, 220 and the work boxes 110, 210 The isolator system has: a sterilization process of sterilizing the inside of the pass boxes and the work boxes 110, 210 by the sterilization part and a passive decontamination process of sterilizing the inside of the pass boxes 120, 220 by the sterilization part provided for another isolator system.SELECTED DRAWING: Figure 4COPYRIGHT: (C)2016,JPO&INPIT