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Sequestering subunit and related compositions and methods
专利权人:
Garth Boehm
发明人:
Garth Boehm
申请号:
US12766472
公开号:
US08685443B2
申请日:
2010.04.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A sequestering subunit comprising an aversive agent and a blocking agent, wherein the blocking agent substantially prevents release of the aversive agent from the sequestering subunit in the gastrointestinal tract for a time period that is greater than 24 hours a composition comprising a sequestering subunit in releasable form, wherein, optionally, the mechanical fragility of the sequestering subunit is the same as the mechanical fragility of the therapeutic agent in releasable form a capsule or tablet comprising a sequestering subunit and a therapeutic agent and a method of preventing abuse of a therapeutic agent.
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