The invention relates to a composition based on a mixture of different olive oils, preferably ecologically cultivated virgin and extra virgin olive oils, and to the use thereof for treating or preventing different disorders in humans and animals. In addition, the invention relates to a dermatologic/dermocosmetic preparation comprising the composition of the invention and to the use thereof for the treatment of skin disorders in humans and animals. In these systemic and/or skin disorders underlying metabolic and immuno-inflammatory-oxidative alterations exist that can be positively modified through the systemic use (oral) or topical use (cutaneous) of the composition of the present invention. The special physical-chemical structure of the composition allows for improved digestive and cutaneous conditions.