This creation discloses a kind of physiological signal sensing device, with the electro-cardio signal of the instantaneously sense person under test of what and is transmitted to a portable electronic devices. Physiological signal sensing device includes a sensor body, one first electrocardio sensing unit, one second electrocardio sensing unit, an electro-cardio signal processor, an analog signal transmission interface and a display unit. Measured electro-cardio signal can carry out carrying out signal processing Hou via electro-cardio signal processor, portable electronic devices are transmitted to via analog signal transmission interface and carry out interpretation and storage what portable electronic devices, have effects that easy to operate, plug and play, at-once monitor.本創作揭露一種生理訊號感測裝置,用於即時感測一待測者之心電訊號並傳輸至一可攜式電子裝置。生理訊號感測裝置包括一感測器本體、一第一心電感測單元、一第二心電感測單元、一心電訊號處理器、一類比訊號傳輸介面以及一顯示單元。所測得之心電訊號可經由心電訊號處理器進行進行訊號處理後,經由類比訊號傳輸介面傳輸至可攜式電子裝置進行判讀及儲存於可攜式電子裝置,其具有操作簡便、隨插即用、即時監測的功效性。