PROCESS FOR PREPARING CABAZITAXEL AND ITS SOLVATE

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专利权人:

发明人:

SRIRAM RAMPALLI,PRADEEP POTHANA,VIJAYA MURALI MOHANRAO SESHAGIRI,CHATURVEDI AKSHAY KANT

申请号：

IN5464/CHE/2012

公开号：

IN2012CH05464A

申请日:

2012.12.27

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

The present invention provides (2α,5β,7β,10β,13α)-4-acetoxy-13-({(2R,3S)-3[ (tert-butoxy carbonyl) amino] -2-hydroxy-3 -phenylpropanoyl} oxy)-1 -hydroxy-7,10-dimethoxy-9-oxo-5,20-epoxytax-1 l-en-2-yl benzoate or Cabazitaxel (I) stable crystalline Form-SC and process for its preparation. The present application also provides Cabazitaxel (I) crystalline Form-SC useful as an active pharmaceutical ingredient in pharmaceutical composition comprising thereof and having anti-cancer activity.

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