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Quinazolinone derivatives as phosphatidylinositol 3-kinase inhibitors
专利权人:
GILEAD SCIENCES INC.
发明人:
Phillips, Barton,Patel, Leena,Treiberg, Jennifer,Perreault, Stephane,Kaplan, Joshua,Phillips, Gary,Yeung, Suet,Evarts, Jerry
申请号:
NZ72605515
公开号:
NZ726055A
申请日:
2015.06.10
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
The present application provides compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein X, Y, Z, n, m’, A’, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidyiinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.
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