N - ((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl) methyl) -5- (ethyl (tetrahydro-2H-pyran-4-yl) amino) -4-methyl-4 - (morphophinomethyl) - [1,1'-biphenyl] -3-carboxamide hydrobromide for use in the treatment of a disease with cell proliferation in the hematological system.
KUNTZ, Kevin Wayne,HUANG, Kuan-chun,CHOI, Hyeong Wook,SANDERS, Kristen,MATHIEU, Steven,CHANDA, Arani,FANG, Frank
申请号:
DK16191716
公开号:
DK3184523T3
申请日:
2013.04.11
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide hydrobromide for use in the treatment of a cell proliferative disorder of the hematologic system. Also provided herein is a particular polymorph form of this compound and its use.