STEPHEN FREDERICK MOSS,ANTOINETTE WILSON,STEVEN JAMES STANWAY,ESTHER DUPERCHY,STEVEN BOAKES,MONA SIMONOVIC,MICHAEL DAWSON,PAMELA BROWN
申请号：
ARP150103879
公开号：
AR102830A1
申请日:
2015.11.26
申请国别(地区):
AR
年份:
2017
代理人:
摘要：
A compound is provided and used for a treatment method, including the treatment of bacterial infection. A method for preparing formula compound (1) is also provided. 1. Claim 1: a formula compound (1),Where: - t is rt-x -；A1 - missing or other amino acids； a2 - other amino acids selected from trinitrate and SERINA, such as l-treonina and l-serina； A3 - other amino acids represented by the formula (2),Where the asterisk is A-a-a-aand -R³ is C₁₋₆ alkyl,Such as c83218331；One or more hydroxy substitutes； - x-es C (o) -,-NHC (O) -,-OC (o)..-CH₂- or -SO₂-；-RT is a terminal group containing hydroxyl and / or amino functions, where - A1 - does not exist, rt-x - is not a residual a-amino acid, there is a free a-amino acid group (- nh832222)；a. The remaining a-amino acids were selected from a group consisting of a, Ser, THR, Val, Leu, LLE, pro, Phe, Tyr, Trp, his, Lys, Arg, acid A, g-diaminotrico (DAB) and a, b-diamonologic (DAP)；-R8310a, together with the attached carbon carbon carbon carbon carbon carbon carbon carbon carbon compound A, is a residual amino acid； r8311, together with the attached carbon carbon carbon carbon carbon carbon carbon carbon carbon carbon compound A, is a residual amino acid； and - r8310, together with the attached carbon carbon carbon carbon carbon carbon carbon carbon carbon carbon carbon carbon group, is not other phenyl； The carbon related nitrogen and carbon groups in leucina o valina and / or o-r8311 do not constitute the remaining leukocytes, ISO leucina, fenillanina, trenina, valina or nor valina； r183044, together with the carbon and nitrogen groups in the carbon carbon group, constitutes the remaining trenina or leucina； and salt, solvatos,Form of protection and / or form of protection.Se proporciona un compuesto y su uso en métodos de tratamiento, incluyendo el tratamiento de infecciones bacterianas. Se proporcionan también métodos para la preparación del compuesto de la fórmula (1). Reivindicación 1: Un compuesto de la fórmula (1), dond
