Jeffrey N. MINER,Mark S. CHAPMAN,Barry QUART,Alex ADJEI,Chunrong YU
申请号:
US14708891
公开号:
US20160271122A1
申请日:
2015.05.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases including VEGFR1-3 and PDGFR-β. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.