ANTIBODY CONSTANT REGION VARIANT

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

KURAMOCHI, TAICHI,IGAWA, TOMOYUKI,MAEDA, ATSUHIKO,MIMOTO, FUTA

申请号：

EP11750823

公开号：

EP2543730A4

申请日:

2011.03.04

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present inventors carried out dedicated research to generate antibody constant regions with reduced Fc³ receptor-binding activity by altering amino acid sequences in the antibody constant region. As a result, the present inventors successfully identified novel constant region sequences with reduced Fc³ receptor-binding activity compared to conventional antibody constant regions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/