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AUTOTAXIN PATHWAY MODULATION AND USES THEREOF
专利权人:
B.S.R.C. "Alexander Fleming"
发明人:
Vassilios Aidinis
申请号:
US13693329
公开号:
US20130202614A1
申请日:
2012.12.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are methods for preventing, treating, or reducing symptoms of a disorder involving the autotaxin (ATX) pathway. In one embodiment, the method features administering to a mammal a sufficient amount of an autotaxin (ATX) or lysophosphatidic acid (LPA) signaling inhibitor, to prevent, treat or reduce symptoms of an inflammatory disorder, autoimmune disorder, fibrosis or malignancy of the lung. Further disclosed are methods for diagnosing an autotaxin-related disorder as well as kits for performing the methods of the invention.
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