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Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
专利权人:
Teva Pharmaceutical Industries Ltd.
发明人:
Kasper, Lloyd H.,Smith, Jacqueline Y.
申请号:
AU2011313842
公开号:
AU2011313842B2
申请日:
2011.10.10
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
A method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis with a pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier, comprising the steps of determining whether the human subject is a glatiramer acetate responder by evaluating a biomarker selected from the group consisting of IL-17 concentration, TNF-a concentration, IL-2 concentration and IFN-γ concentration, or a combination thereof, in the blood of the human subject and administering the pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier to the human subject only if the human subject is identified as a glatiramer acetate responder.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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