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MODULATION DES RECEPTEURS COUPLES AUX PROTEINES G (RCPG) PAR LES IMIPRIDONES
专利权人:
INC.;ONCOCEUTICS
发明人:
ALLEN, JOSHUA E.,STOGNIEW, MARTIN,PRABHU, VARUN VIJAY
申请号:
CA3013044
公开号:
CA3013044A1
申请日:
2017.01.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Imipridones has been found to selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and to be useful for the treatment of conditions and disorders in need of such modulation, such as cancers, psychiatric disorders, and bacterial infections. In addition, methods of identifying whether a subject having these condition, is likely to be responsive to a treatment regimen, such as administration of an imipridone, are provided. Furthermore, methods of assessing the effectiveness of a treatment regimen, such as administration of an imipridone, monitoring, or providing a prognosis for a subject with these condition are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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