JOHNS HOPKINS UNIVERSITY;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人:
LAI, SAMUEL,WANG, YING-YING,KANNAN, ARTHI,NUNN, KENNETTA,SUBRAMANI, DURAI BABU,CONE, RICHARD
申请号:
EP13851374
公开号:
EP2912060A4
申请日:
2013.10.29
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus.