David B. Wurn,David A. Wilson,Bruce A. Barner,Cynthia L. Rand,Matthew D. Miller,Michael J. Johnson
申请号：
US12810962
公开号：
US08497303B2
申请日:
2009.01.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A method to enhance solubility of an active compound comprises combining an active compound, having an aqueous solubility that is less than or equal to about 10 mg/mL, and an amount of methoxypolyethylene glycol that is sufficient to increase the aqueous solubility of the active compound. Enhancement of aqueous solubility for this combination may be significantly greater than that of an active compound in combination with an equivalent amount of polyethylene glycol. Particularly enhanced solubility is shown where a small amount of water is also included. The invention may be used in a wide variety of applications, such as for pharmaceutical, agricultural, antimicrobial, and personal care products.
