Polymorphs of deuterated omega-diphenylurea or salts thereof

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专利权人:

发明人:

Weidong Feng

申请号：

US15414813

公开号：

US09889123B2

申请日:

2017.01.25

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention relates to polymorphs of deuterated omega-diphenylurea or salts thereof. In particular, the invention provides polymorphs of 4-(4-{3-[4-chloro-3-(trifluoromethyl)phenyl)-ureido]-phenoxy}-2-(N-1′,1′,1′-trideutero-methyl)picolinamide or its salt, namely, polymorphs of the compound as shown in formula (I) or its salt. The polymorphs are suited for preparing the pharmaceutical composition used for inhibiting phosphokinase (such as raf kinases).

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