PROBLEM TO BE SOLVED: To determine tiredness in which a possibility of a feeling of the tiredness being masked is high, and which is hardly realized.SOLUTION: A biological state estimation device 100 includes: biological adjustment function element determination means 200 for analyzing a biological signal and obtaining a plurality of indexes involved in a biological adjustment function including indexes with high relevance to an autonomic nervous function, and physical and mental tiredness or feelings and feeling-of-tiredness estimation means 300 for combining the plurality of indexes obtained by the biological adjustment function element determination means 200, and estimating whether or not the biological state is the state in which masking of a feeling of tiredness is generated.SELECTED DRAWING: Figure 2COPYRIGHT: (C)2018,JPO&INPIT【課題】 疲労感のマスキングの可能性が高く、自覚しにくい疲労の判定を可能にする。【解決手段】 本発明の生体状態推定装置100は、生体信号を分析して、自律神経機能、肉体・精神疲労又は感覚との関連性の高い指標を含む、生体調節機能に関与する複数の指標を求める生体調節機能要素判定手段200と、前記生体調節機能要素判定手段200により求められた複数の指標を組み合わせて、前記生体状態として、疲労感のマスキングが生じている状態であるか否かを推定する疲労感推定手段300とを含む。【選択図】 図2