Cosmetic compositions comprising an extract ofMelicope hayesiiand methods of using such compositions to impart anti-aging benefits to the skin are disclosed. These compositions are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging.本發明揭示一種包含蜜茱萸(Melicope hayesii)萃取物之化妝品組合物及利用該等組合物賦予皮膚抗老化效益之方法。據信此等組合物具有阻遏至少一種涉及皮膚老化之生物化學路徑之調節活性。