The present invention relates to an injection agent composition for local fat decomposition without pain, edema, or other side effects and a preparing method thereof. More specifically, the injection agent composition includes phosphatidylcholine (PPC) and a glycocholic acid (or a salt thereof) or a tauric acid (or a salt thereof) at a specific blending ratio to prevent side effects including pain, edema, necrosis of muscle cells, fibroblasts, or endothelial cell in fat cells, and without numbness in administration sites, significant swelling, erythema, hardening, sensory abnormalities, nodules, itchiness, burning sensations, nerve damage, or dysphagia. The composition of a single deoxycholic acid (DCA) injection agent or a PPC injection agent blended with the DCA as a solubilizer, which are known as conventional local fat reduction injection agents dissolves fibroblasts, vascular endothelial cells, and skeletal muscle cells as well as fat cells to cause pain, numbness, significant swelling, local edema, erythema, hardening, sensory abnormalities, nodules, itchiness, burning sensation, and dysphagia due to the inevitable cell necrosis, thereby making patients suffer pain, discomfort, and anxiety while having low compliance with medication. According to the present invention, the injection agent composition for local fat reduction can be safe and stable, executes the lipolysis operation selectively to decompose the fat cells selectively, and excellently induce the apoptosis of the fat cells, thereby improving the compliance with medication and quality of life for patients in an excellent manner without the above-described side effects.본 발명은, 통증, 부종 및 부작용이 없는 국소지방 분해용 주사제 조성물과 이의 제조방법에 관한 것으로, 보다 상세하게는 글리코콜린산(또는 이의 염) 또는 타우로콜린산(또는 이의 염)과 포스파티딜콜린(PPC)을 특정 배합비로 포함하여 통증과 부종 그리고 지방세포 외 근육세포, 섬유아세포 및 혈관내피세포 괴사, 투여부위의 무감각증, 광범위한 종창, 홍반, 경화, 감각이상, 결절, 가려움증, 작열감, 신경손상 및 연하곤란 등의 부작용이 없는 국소지방 감소용 주사제 조성물과 상기 조성물의 제조방법에 대한 것이다. 기존의 국소 지방 감소용 주사제로서 알려진 DCA 단독주사제 또는 가용화제로 DCA가 배합된
