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Microvesicle ,and manufacturing method for same
专利权人:
发明人:
LI ZHONG,KATSURA MISAKO,FENG LUO
申请号:
IN9339/DELNP/2015
公开号:
IN2015DN09339A
申请日:
2015.10.08
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides: a manufacturing metnod for microvesicles containing lentivirus R A having a transgenic product and/or a transgene, the method including a step in which cells are cultured after having a transgene introduced thereto using a lentivirus vector :from wmch at least one structural protein gene has been deleted, and which contains a transgene under the control of a telomerase reverse transcriptase (TERT) gene promoter in the lentivirus genome sequence, and then microvesicles containing the lentivirus RNA having a transgenic product and/or transgene are released to the outside of the cell, and a step i n which the released microvesicles are collected; microvesicles obtained using said method; and uses for said microvesicles.
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