Yu Kyeong HWANG,Sung Yoo CHO,Sung Yong WON,Ho Yong LIM,Jung Hyun HER,Mi Young JUNG,Hyun Ah KIM,Su Hyun GWON,Eun Sol LEE,Han Sol KIM
申请号：
US16474426
公开号：
US20190336533A1
申请日:
2017.12.28
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides a chimeric antigen receptor and natural killer cells expressing the same, and particularly, a chimeric antigen receptor (CAR) which includes an intracellular signaling domain including the whole or a portion of an OX40 ligand (CD252), thereby having excellent effects of increasing anticancer activity of immune cells, and immune cells expressing the same.
