INSTITUTE FOR BASIC SCIENCE;KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人:
Gou Young KOH,Jaeryung KIM,Do Young PARK
申请号：
US16473685
公开号：
US20190330324A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a composition which is for preventing and treating eye diseases and comprises an anti-angiopoietin-2 (Ang2) antibody and, more specifically, to a novel use of an anti-Ang2 antibody as an agent for preventing or treating eye diseases, wherein the anti-Ang2 antibody is specifically coupled to Ang2, is coupled to a Tie2 receptor together with Ang2, and has improved affinity. The composition according to the present invention can be usefully used to develop a treatment agent for macular degeneration, diabetic retinopathy, and glaucoma.
