COMPOSITIONS AND METHODS FOR SIRNA INHIBITION OF ANGIOPOIETIN 1 AND 2 AND THEIR RECEPTOR TIE2

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专利权人:

Samuel Jotham Reich;Michael J. Tolentino

发明人:

Samuel Jotham Reich,Michael J. Tolentino

申请号：

US13163806

公开号：

US20120039986A1

申请日:

2011.06.20

申请国别(地区):

US

年份:

2012

代理人:

摘要：

RNA interference using small interfering RNAs which are specific for mRNA produced from the Ang1, Ang2 or Tie2 genes inhibits expression of these genes. Diseases which involve Ang1, Ang2 or Tie2 mediated angiogenesis, such as inflammatory and autoimmune diseases, diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.

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中国工程科技知识中心

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