KIM, NORMAN, N.,MCVICAR, WILLIAM, K.,MCCAULEY, THOMAS, G.,JAGTAP, PRAKASH
申请号：
EP11760319
公开号：
EP2569325A4
申请日:
2011.03.25
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing and/or controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).
