Refers to a polypeptide against a tumor caused by the Epstein Barr Virus (EBV) comprising the amino acid sequence of SEQ ID no. 29 is formed by means of Union operations of a Mutant polypeptide of colicin was obtained by mutation of amino acid residues of g11a, h22g, a26g,V31l and h40d in the Peptide Chain of colicin types natural and can form ion channels with a polypeptide of anti EB virus Antibody whose Amino Acid Sequence is the same as that of polypeptide secreted by the hybridoma monoclonal antibody of TCCA HB - 168 or a polypeptide of my Meticos of anti EB virus Antibody.It also relates to a Pharmaceutical composition useful in the treatment of tumor caused by EB virusSE REFIERE A UN POLIPEPTIDO CONTRA UN TUMOR CAUSADO POR EL VIRUS DE EPSTEIN-BARR (EB) QUE COMPRENDE LA SECUENCIA DE AMINOACIDOS DE SEQ ID Nº 29 QUE SE FORMA MEDIANTE UNION OPERATIVA DE UN POLIPEPTIDO MUTANTE DE COLICINA QUE SE OBTIENE MEDIANTE MUTACION DE RESIDUOS DE AMINOACIDO DE G11A, H22G, A26G, V31L Y H40D EN LA CADENA PEPTIDICA DE COLICINA DE TIPO NATURAL Y QUE PUEDE FORMAR CANALES IONICOS CON UN POLIPEPTIDO DE ANTICUERPO ANTI-VIRUS EB CUYA SECUENCIA DE AMINOACIDOS ES LA MISMA QUE LA DEL POLIPEPTIDO DE ANTICUERPO MONOCLONAL SECRETADO POR EL HIBRIDOMA DE ATCC HB-168 O UN POLIPEPTIDO DE MIMETICOS DE ANTICUERPO ANTI-VIRUS EB. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA UTIL EN EL TRATAMIENTO DE TUMOR CAUSADO POR EL VIRUS EB
