YOSHIDA HIROKO,OHTSUKA TOSHIAKI,TAKIZAWA TAKESHI,MATSUI YUMI,OGUNI AKIKO,MATSUOKA TATSUJI
申请号：
NZ62334711
公开号：
NZ623347A
申请日:
2011.10.27
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is an antibody characterized in that:, a heavy chain sequence contains a variable region having CDRH1, CDRH2, and CDRH3, and the CDRH1 comprises an amino acid sequence represented by SEQ ID NO: 82 (GYFMN), the CDRH2 comprises either one of the amino acid sequences represented by SEQ ID NOS: 83 and 89 (RFNPYNXDTFYNQKFKG), and the CDRH3 comprises an amino acid sequence represented by SEQ ID NO: 84 (SAYYFDSGGYFDY) and, a light chain sequence contains a variable region having CDRL1, CDRL2, and CDRL3, and the CDRL1 comprises anyone of the amino acid sequences represented by SEQ ID NOS: 79, 85, 86, 87, and 88 (RSSQSLVHSNXNTYLH), the CDRL2 comprises an amino acid sequence represented by SEQ ID NO: 80 (KVSNRFS), and the CDRL3 comprises an amino acid sequence represented by SEQ ID NO: 81 (SQSTHVPWT), or a functional fragment of the antibody., Further disclosed are antibodies which compete for binding with said antibodies or which bind the same epitope thereof.
