B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY;THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
发明人:
Varda Shoshan-Barmatz
申请号：
US15868252
公开号：
US10385104B2
申请日:
2018.01.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to peptides comprising analogues of VDAC1-derived peptides having improved pharmacokinetic characteristics compared to the native parent peptides, which are effective in impairing cell energy production, in inducing apoptosis and cell death, particularly of cancerous cells, in eliminating cancer stem cells and in reducing symptoms associated with fat accumulation in liver cells particularly with nonalcoholic fatty liver disease (NAFLD) and symptoms associated thereto.
