Matthias Grauert,Daniel Bischoff,Georg Dahmann,Raimund Kuelzer,Klaus Rudolf
申请号：
US13739059
公开号：
US08889677B2
申请日:
2013.01.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates to compounds of formula Itheir use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.
