Provided are methods of modulating glutamine synthetase activity in a plant, particularly weeds, by applying to the plant or substrate for growing the plant a microorganism (e.g. Burkholderia strain), or a supernatant, cell fraction, filtrate, extract, or a compound derived from the microorganism, in an amount effective to modulate glutamine synthetase activity. Also provided are methods for identification of plant glutamine synthetase inhibitors.本發明提供調節植物、尤其野草中之麩醯胺酸合成酶活性之方法,其是藉由向該植物或用於生長該植物之基質施用對調節麩醯胺酸合成酶活性有效之量的微生物(例如伯克霍爾德氏菌(Burkholderia)菌株),或源自該微生物之上清液層、細胞溶離份、濾液、提取物或化合物而達成。亦提供鑑定植物麩醯胺酸合成酶抑制劑之方法。
