Semi-Synthetic GLP-1 Peptide-FC Fusion Constructs, Methods and Uses

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专利权人:

George Heavner

发明人:

George Heavner

申请号：

US13422196

公开号：

US20120189627A1

申请日:

2012.03.16

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention relates to semi-synthetic biologic molecules which are conjugates of GLP-1 peptides and human multimeric proteins or protein fragments, such as an antibody Fc joined by a non-peptidyl bond. The constructs demonstrate biological activity and are useful making therapeutic compositions and therapeutic formulations for use in treating diseases characterized by lack of glycemic control.

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