REDUCTION DE LA CHARGE TUMORALE PAR L'ADMINISTRATION D'ANTAGONISTES DE CCR1 EN ASSOCIATION AVEC DES INHIBITEURS DE PD-1 OU DES INHIBITEURS DE PD-L1

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专利权人:

INC.;CHEMOCENTRYX

发明人:

CHARO, ISRAEL,JUNG, HEIYOUN,SCHALL, THOMAS J.,ZHANG, PENGLIE

申请号：

CA3019391

公开号：

CA3019391A1

申请日:

2017.04.06

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides methods for reducing tumor burden, tumor growth, tumor progression, and/or metastasis in a subject suffering from a solid tumor cancer such as triple negative breast cancer. The methods include administering to a subject in need thereof a therapeutically effective amount of a PD-Ll inhibitor or a PD-1 inhibitor in combination with a small molecule chemokine receptor antagonist that blocks CCR1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/