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Method of treating cancer with Dll4 antagonist and chemotherapeutic agent
专利权人:
Inc.;Regeneron Pharmaceuticals
发明人:
Noguera-Troise, Irene,Thurston, Gavin,Thibault, Alain
申请号:
AU2010266004
公开号:
AU2010266004A8
申请日:
2010.06.25
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention provides methods for treating various types of cancer/tumor by administering the combination of DII4 antagonists, in particular, DII4 antibodies and fragments thereof that specifically bind human DII4, and chemotherapeutic agents. Such combination therapies exhibit synergistic effects compared to the treatment with either agent alone. Thus, the methods of the invention are particularly beneficial for cancer patients who have low tolerance to the side effects caused by high dosages required for the treatment by either agent alone, by being able to reduce effective dosages. Pharmaceutical compositions and kits containing DII4 antagonists and chemotherapeutic agents are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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