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VACCIN DANS UN VECTEUR RECOMBINANT D'ADÉNOVIRUS AVIAIRE DE SÉROTYPE 9
专利权人:
S.A. de C.V.;Grupo Industrial Pecuario
发明人:
申请号:
EP15829016.3
公开号:
EP3178938A4
申请日:
2015.08.06
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A recombinant vaccine comprising a serotype 9 fowl adenovirus vector (FAdV-9) having at least one exogenous nucleotide sequence inserted encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region, and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the at least one exogenous nucleotide sequence encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region is located between the 491 and 2782 nucleotides. The vector of this vaccine is stable for industrial scale production. Likewise, even when this vaccine is administered in combination with a vaccine against Marek's disease, both vaccines produce an adequate immune response which is not affected by interference between each other. In the same way, effectiveness of the recombinant vaccine is not affected by maternal antibodies, and is capable of inducing both an early and lasting protective response, even with only one application.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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