The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an anti-inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide that has at least one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.本發明關於具有抗發炎活性的胜肽,其中該胜肽包含序列編號:1至序列編號:161中之任何一個胺基酸序列;該胜肽具有與上述序列具有80%以上之同源性的胺基酸序列;或該胜肽為上述胜肽的片段。本發明也關於包含上述胜肽的抗發炎成分。根據本發明,具有序列編號:1至序列編號:161中之至少一個胺基酸序列的胜肽對抑制發炎及以預防性手段抑制發炎二者皆具有優異的功效。因此,包含此發明之胜肽的成分可被用作抗發炎醫藥成分或用作化妝品成分,從而治療或防止多種不同類型的發炎疾病。