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POLYMERIC SYNTHETIC ANTIDOTE
专利权人:
UNIVERSITE DE LIEGE
发明人:
Christian GRANDFILS,Lucas FLEBUS,Chantal SEVRIN
申请号:
US14911435
公开号:
US20160193246A1
申请日:
2014.08.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A polymer of formula (I) where X1 and X2 respectively represent the alpha and omega end groups of the polymer; R1 represents a hydrogen atom or a straight or branched chain alkyl group; R2 represents a straight or branched chain alkyl group which is substituted by a group which may have a positive charge at physiological pH; and n represents the number of repetitive units of the polymer, or a copolymer thereof; for use as a medicament and for treatment of a heparin overdose wherein the polymer of formula (I) has been found to have a selectivity and affinity for heparin.
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