One method for supporting a patient through a treatment regimen includes: accessing a log of use of a native communication application executing on a mobile computing device by a patient； selecting a subgroup of a patient population based on the log of use of the native communication application and a communication behavior common to the subgroup； retrieving a regimen adherence model associated with the subgroup, the regimen adherence model defining a correlation between treatment regimen adherence and communication behavior for patients within the subgroup； predicting patient adherence to the treatment regimen based on the log of use of the native communication application and the regimen adherence model； and presenting a treatment-related notification based on the patient adherence through the mobile computing device.
