Procédé de ciblage de populations de cellules spécifiques au moyen de conjugués maytansinoïdes d'agents de liaison cellulaire liés par un lien non clivable, lesdits conjugués et procédés de fabrication desdits conjugués
The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a non-cleavable linker and the cell-binding agent binds to cells of the selected cell population.