ANDREW THOMPSON,CAROL LAMBERSON,SCOTT GREENFIELD,RAJENDRA PARASMAL,REMY ANGELAUD
申请号:
PT11748095
公开号:
PT2538785T
申请日:
2011.02.24
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds, such as compounds of the formula: wherein X, Y 1 , Y 2 , R 1 , and R 2 are as defined herein. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.