An actuator housing (100) for use with a metered dose inhaler (MDI) device which comprises a housing portion (115) having a nozzle block (130) in which an actuator seat (135) and an actuator nozzle (145) are formed. The housing portion has an axis (120) which is angled with respect to a vertical plane which is perpendicular to a base portion or thumb grip (150) formed at a closed end thereof. A mouthpiece portion (125) is joined to the housing portion which has a roof section (180) and a floor section (125b). The roof section is angled upwards with respect to the floor portion, and provides a cross-piece (185) with which teeth of a patient can engage. Such an actuator housing addresses problems associated with buccal and tongue deposition of medicaments, as a spray of medicament from the actuator nozzle is directed over the tongue and into the airway.