Alan Daniel Brown;Robert Ian Storer;Andrew Simon Bell;Russell Andrew Lewthwaite;Manuel Perez Pacheco;Nunzio Sciammetta;David James Rawson;David Simon Millan;Nigel ;Ian Roger Marsh;Paul Anthony Stupple
发明人:
Andrew Simon Bell,Alan Daniel Brown,Russell Andrew Lewthwaite,Ian Roger Marsh,David Simon Millan,Manuel Perez Pacheco,David James Rawson,Nunzio Sciammetta,Robert Ian Storer,Paul Anthony Stupple,Nigel
申请号：
US13179585
公开号：
US08685977B2
申请日:
2011.07.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I):or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description.Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
