VISHNU DATT SHARMA,DEVENDRA SINGH CHAUHAN,RAHUL SHARMA,HIRAWATI,VISHWA MOHAN KATOCH,KIRAN KATOCH,KRISHNAMURTHY VENKATESAN
申请号:
IN884/DEL/2007
公开号:
IN280840B
申请日:
2007.04.23
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention identifies set of primers used in the classification of potential drug target genes in leprosy genome. These genes have been selected from human on the basis of their over expression during the active stage of disease as compared to other selected genes of metabolism of the organism and having less then 44% homology within the human genome. These gene targets are used to find out the bacterial specific blocker to act as bactericidal drug by in-silico proteomic approaches (protein modeling and chemical database search).These gene targets could have broader application for drug development for tuberculosis and other mycobacterial diseases.