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COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID
专利权人:
ADOCIA
发明人:
Alexandre GEISSLER
申请号:
US16213881
公开号:
US20190275108A1
申请日:
2018.12.07
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A composition in the form of an injectable aqueous solution, the pH of which is comprised from 6.0 to 8.0, including at least:a) amylin, an amylin receptor agonist or an amylin analogue;b) a co-polyamino acid bearing carboxylate charges and hydrophobic radicals Hy, said co-polyamino acid being constituted of glutamic or aspartic units and said hydrophobic radicals Hy being according to formula I below:*GpRrGpAaGpC)p  ; ;Formula Iwherein the composition does not comprise a basal insulin the isoelectric point pI of which is comprised from 5.8 to 8.5. It also relates to a composition wherein it further includes prandial insulin.
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