DOMINGUEZ, Esteban,GUO, Deqi,MADER, Mary Margaret,NGUYEN, Anh-Quan Hannah,DEL PRADO, Miriam Filadelfa,RICHETT, Michael Enrico,RODRIGUEZ, Michael John,YIP, Yvonne Yee Mai,YU, Kuo-Long
申请号:
PH12018500423
公开号:
PH12018500423A1
申请日:
2018.02.26
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
The present invention relates to compounds that inhibit activity of the histone lysine methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, such as hematologic and solid tumors.