Daniël VERHOEF,Pieter H. REITSMA,Mettine H. A. BOS
申请号:
US15313881
公开号:
US20170157223A1
申请日:
2015.05.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This disclosure relates to recombinant FXa polypeptides that can be used as antidotes to completely or partially reverse an anti-coagulant effect of a coagulation inhibitor in a subject, preferably a direct factor Xa inhibitor. Disclosed herein are recombinant factor Xa proteins and a method of completely or partially reversing an anti-coagulant effect of a coagulation inhibitor in a subject.